A-Level Biology Specification

Edexcel B 9BI0

Section 7.2: Factors affecting gene expression

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#7.2i

Know that transcription factors are proteins that bind to DNA.

#7.2ii

Understand the role of transcription factors in regulating gene expression.

#7.2iii

Understand how post–transcription modification of mRNA in eukaryotic cells (RNA splicing) can result in different products from a single gene.

#7.2iv

Understand that gene expression can be changed by epigenetic modification, including non-coding RNA, histone modification and DNA methylation.

#7.2v

Know that epigenetic modification is important in ensuring cell differentiation.