A-Level Biology Specification

AQA 7402

Section 8.2.3: Gene expression and cancer

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#8.2.3.1

The main characteristics of benign and malignant tumours.

#8.2.3.2

The role of the following in the development of tumours:

- tumour suppressor genes and oncogenes
- abnormal methylation of tumour suppressor genes and oncogenes
- increased oestrogen concentrations in the development of some breast cancers.

#8.2.3.3

Students should be able to:

- evaluate evidence showing correlations between genetic and environmental factors and various forms of cancer
- interpret information relating to the way in which an understanding of the roles of oncogenes and tumour suppressor genes could be used in the prevention, treatment and cure of cancer.