A-Level Biology Specification

AQA 7402

Section 6.4.2: Control of blood glucose concentration

Are you studying this syllabus?

You can track your progress by adding it to your account.

Add syllabus

#6.4.2.1

The factors that influence blood glucose concentration.

#6.4.2.2

The role of the liver in glycogenesis, glycogenolysis and gluconeogenesis.

#6.4.2.3

The action of insulin by:

- attaching to receptors on the surfaces of target cells
- controlling the uptake of glucose by regulating the inclusion of channel proteins in the surface membranes of target cells
- activating enzymes involved in the conversion of glucose to glycogen.

#6.4.2.4

The action of glucagon by:

- attaching to receptors on the surfaces of target cells
- activating enzymes involved in the conversion of glycogen to glucose
- activating enzymes involved in the conversion of glycerol and amino acids into glucose.

#6.4.2.5

The role of adrenaline by:

- attaching to receptors on the surfaces of target cells
- activating enzymes involved in the conversion of glycogen to glucose.

#6.4.2.6

The second messenger model of adrenaline and glucagon action, involving adenylate cyclase, cyclic AMP (cAMP) and protein kinase.

#6.4.2.7

The causes of types I and II diabetes and their control by insulin and/or manipulation of the diet.

#6.4.2.8

Students should be able to evaluate the positions of health advisers and the food industry in relation to the increased incidence of type II diabetes.

#6.4.2P11

Required practical 11

Production of a dilution series of a glucose solution and use of colorimetric techniques to produce a calibration curve with which to identify the concentration of glucose in an unknown ‘urine’ sample.