A-Level Biology Edexcel B 9BI0

7.3: Stem cells

#7.3i

Understand what is meant by a stem cell, including the differences between totipotent, pluripotent and multipotent stem cells.

#7.3ii

Understand that pluripotent stem cells from embryos provide opportunities to develop new medical advances although there are ethical considerations.

#7.3iii

Understand how epigenetic modifications can result in totipotent stem cells in the embryo developing into pluripotent cells in the blastocyst and finally into fully differentiated somatic cells.

#7.3iv

Understand how differentiated fibroblasts can be reprogrammed to form induced pluripotent stem cells (iPS cells) by the artificial introduction of named genes.

#7.3v

Understand why the use of iPS stem cells may be less problematic than the use of embryonic stem cells.

7.2
Factors affecting gene expression
7.4
Gene technology