GCSE Biology Specification

OCR A J247

Section B1.2: What happens in cells (and what do cells need)?

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#B1.2a

describe DNA as a polymer

#B1.2b

describe DNA as being made up of two strands forming a double helix

#B1.2c

describe that DNA is made from four different nucleotides; each nucleotide consisting of a common sugar and phosphate group with one of four different bases attached to the sugar

the pairs of complementary bases (A-T and G-C)

#B1.2d

recall a simple description of protein synthesis

the unzipping of the DNA molecule around the gene, copying to mRNA in nucleus (transcription), (translation) of the nucleotide sequence, in the cytoplasm

#B1.2e

explain simply how the structure of DNA affects the proteins made in protein synthesis

triplet code and its use to determine amino acid order in a protein

#B1.2f

describe experiments that can be used to investigate enzymatic reactions

#B1.2g

explain the mechanism of enzyme action

the role of enzymes in metabolism, the role of the active site, enzyme specificity (lock and key hypothesis) and factors affecting the rate of enzyme controlled reactions (pH, temperature, substrate and enzyme concentration)