GCSE Biology Specification

AQA 8461

Section 4.2: Respiration

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#4.2.1

Aerobic and anaerobic respiration

Students should be able to describe cellular respiration as an exothermic reaction which is continuously occurring in living cells.

The energy transferred supplies all the energy needed for living processes.

Respiration in cells can take place aerobically (using oxygen) or anaerobically (without oxygen), to transfer energy.

Students should be able to compare the processes of aerobic and anaerobic respiration with regard to the need for oxygen, the differing products and the relative amounts of energy transferred.

Organisms need energy for:
- chemical reactions to build larger molecules
- movement
- keeping warm.

Aerobic respiration is represented by the equation:
glucose + oxygen → carbon dioxide + water

Students should recognise the chemical symbols: CO2, H2O, O2 and C6H12O6.

Anaerobic respiration in muscles is represented by the equation:
glucose → lactic acid

As the oxidation of glucose is incomplete in anaerobic respiration much less energy is transferred than in aerobic respiration.

Anaerobic respiration in plant and yeast cells is represented by the equation:
glucose → ethanol + carbon dioxide

Anaerobic respiration in yeast cells is called fermentation and has economic importance in the manufacture of bread and alcoholic drinks.

#4.2.2

Response to exercise

During exercise the human body reacts to the increased demand for energy.

The heart rate, breathing rate and breath volume increase during exercise to supply the muscles with more oxygenated blood.

If insufficient oxygen is supplied anaerobic respiration takes place in muscles. The incomplete oxidation of glucose causes a build up of lactic acid and creates an oxygen debt. During long periods of vigorous activity muscles become fatigued and stop contracting efficiently.


Blood flowing through the muscles transports the lactic acid to the liver where it is converted back into glucose. Oxygen debt is the amount of extra oxygen the body needs after exercise to react with the accumulated lactic acid and remove it from the cells.

#4.2.3

Metabolism

Students should be able to explain the importance of sugars, amino acids, fatty acids and glycerol in the synthesis and breakdown of carbohydrates, proteins and lipids.

Metabolism is the sum of all the reactions in a cell or the body.

The energy transferred by respiration in cells is used by the organism for the continual enzyme controlled processes of metabolism that synthesise new molecules.

Metabolism includes:
- conversion of glucose to starch, glycogen and cellulose
- the formation of lipid molecules from a molecule of glycerol and three molecules of fatty acids
- the use of glucose and nitrate ions to form amino acids which in turn are used to synthesise proteins
- respiration
- breakdown of excess proteins to form urea for excretion.

All of these aspects are covered in more detail in the relevant specification section but are linked together here.