A-Level Biology Specification

AQA 7402

Section 1.5.1: Structure of DNA and RNA

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#1.5.1.1

Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are important information-carrying molecules. In all living cells, DNA holds genetic information and RNA transfers genetic information from DNA to the ribosomes.

#1.5.1.2

Ribosomes are formed from RNA and proteins.

#1.5.1.3

Both DNA and RNA are polymers of nucleotides. Each nucleotide is formed from a pentose, a nitrogen-containing organic base and a phosphate group:

#1.5.1.4

The components of a DNA nucleotide are deoxyribose, a phosphate group and one of the organic bases adenine, cytosine, guanine or thymine.

#1.5.1.5

The components of an RNA nucleotide are ribose, a phosphate group and one of the organic bases adenine, cytosine, guanine or uracil.

#1.5.1.6

A condensation reaction between two nucleotides forms a phosphodiester bond.

#1.5.1.7

A DNA molecule is a double helix with two polynucleotide chains held together by hydrogen bonds between specific complementary base pairs.

#1.5.1.8

An RNA molecule is a relatively short polynucleotide chain.

#1.5.1.9

Students should be able to appreciate that the relative simplicity of DNA led many scientists to doubt that it carried the genetic code.