A-Level Biology Specification

OCR B H422

Section 3.2.2: The immune system

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#3.2.2a

primary defences and non-specific defences against pathogens

Primary defences to include mucus and cilia in the respiratory tract, lysozyme in tears and stomach acid AND non-specific immune responses to include phagocytosis and inflammation.

#3.2.2b

the mode of action of phagocytes

To include the roles of cytokines, opsonins, phagosomes and lysosomes.

#3.2.2c

the different roles and modes of action of B and T lymphocytes in the specific immune response

To include clonal selection and clonal expansion, plasma cells, T helper cells, T killer cells and T regulatory cells.

#3.2.2d

the secondary immune response and the role of memory cells in long term immunity

To include T memory cells and B memory cells.

#3.2.2e

the structure and general function(s) of antibodies

To include descriptions of antibody structure from diagrams AND an outline of the action of opsonins and agglutinins.

#3.2.2f

how individuals can be tested for TB and HIV infection

To include antibody tests and antigen tests for both diseases AND the Mantoux test for TB.

#3.2.2g

the differences between active and passive immunity, and between natural and artificial immunity

To include examples of each type of immunity.

#3.2.2h

how allergies can result from hypersensitivity of the immune system

To include an outline of the sequence of events in a typical allergic response to allergens such as pollen (hay fever).