A-Level Biology AQA 7402

8.2.3: Gene expression and cancer

#8.2.3.1

The main characteristics of benign and malignant tumours.

#8.2.3.2

The role of the following in the development of tumours:

  • tumour suppressor genes and oncogenes
  • abnormal methylation of tumour suppressor genes and oncogenes
  • increased oestrogen concentrations in the development of some breast cancers.
#8.2.3.3

Students should be able to:

  • evaluate evidence showing correlations between genetic and environmental factors and various forms of cancer
  • interpret information relating to the way in which an understanding of the roles of oncogenes and tumour suppressor genes could be used in the prevention, treatment and cure of cancer.
8.2.2
Regulation of transcription and translation
8.3
Using genome projects