A-Level Biology AQA 7402

4.1: DNA, genes and chromosomes

#4.1.1

In prokaryotic cells, DNA molecules are short, circular and not associated with proteins.

#4.1.2

In the nucleus of eukaryotic cells, DNA molecules are very long, linear and associated with proteins, called histones. Together a DNA molecule and its associated proteins form a chromosome.

#4.1.3

The mitochondria and chloroplasts of eukaryotic cells also contain DNA which, like the DNA of prokaryotes, is short, circular and not associated with protein.

#4.1.4

A gene is a base sequence of DNA that codes for:

  • the amino acid sequence of a polypeptide
  • a functional RNA (including ribosomal RNA and tRNAs).
#4.1.5

A gene occupies a fixed position, called a locus, on a particular DNA molecule.

#4.1.6

A sequence of three DNA bases, called a triplet, codes for a specific amino acid. The genetic code is universal, non-overlapping and degenerate.

#4.1.7

In eukaryotes, much of the nuclear DNA does not code for polypeptides. There are, for example, non-coding multiple repeats of base sequences between genes. Even within a gene only some sequences, called exons, code for amino acid sequences. Within the gene, these exons are separated by one or more non-coding sequences, called introns.

3.4.2
Mass transport in plants
4.2
DNA and protein synthesis