A-Level Biology AQA 7402

1.5.2: DNA replication

#1.5.2.1

The semi-conservative replication of DNA ensures genetic continuity between generations of cells.

#1.5.2.2

The process of semi-conservative replication of DNA in terms of:

  • unwinding of the double helix
  • breakage of hydrogen bonds between complementary bases in the polynucleotide strands
  • the role of DNA helicase in unwinding DNA and breaking its hydrogen bonds
  • attraction of new DNA nucleotides to exposed bases on template strands and base pairing
  • the role of DNA polymerase in the condensation reaction that joins adjacent nucleotides.
#1.5.2.3

Students should be able to evaluate the work of scientists in validating the Watson–Crick model of DNA replication.

1.5.1
Structure of DNA and RNA
1.6
ATP